Abnormal laboratory results: BRCA testing for familial breast cancer

BRCA Genetic Testing for Patients With and Without Breast Cancer

Of the more than 200,000 breast cancers diagnosed annually in the United States, 5-10% are associated with obvious hereditary predisposition, which is mostly related to autosomal dominant mutations of the BRCA1 and BRCA2 genes. BRCA1/2 mutations confer an increased lifetime risk for the development of breast cancer (up to 80%), contralateral breast cancer (about 30% at 10 years), ovarian cancer...

investigation of mitochondrial common deletion and brca mutations for detection of familial breast cancers in archival breast cancer materials

abstract bachground and aim: mutation analysis of mitochondrial genome and brca genes are helpful in the early diagnosis of familial breast cancers. in this study, we investigated mitochondrial common deletion and brca mutations through multiplex pcr and clinical parameters for the detection of familial breast cancers in archival breast cancer samples. methods: the multiplex pcr was conducted o...

Communication Patterns in Korean Families during BRCA Genetic Testing for Breast Cancer

www.kons.or.kr | e-ISSN 2093-7776 ISSN 1598-4559 Communication Patterns in Korean Families during BRCA Genetic Testing for Breast Cancer Gwen Anderson · Jun, Myunghee · Choi, Kyung Sook Adjunct Associate Professor, School of Nursing, San Diego State University, CA, USA; Professor, Department of Nursing, Daejeon University, Daejeon; Professor, Department of Nursing, Chung-Ang University, Seoul, ...

Retraction: Relation between HPV genotypes and BRCA mutation in familial breast cancer.

Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: recommendation statement.

This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility, along with the supporting scientific evidence. The complete information on which this statement is based, including evidence tables and references, is included in the evidence synthesis available through the...